Is a bacteria going to make me a mother?
How does microbiota affect fertility?
How does microbiota affect fertility?
Fertility essentials
High-quality embryo
Day 5 blastocyst
Day 3 morula
Healthy endometrium
Minimum thickness of 7 mm
Optimal endometrial environment
Microbiota, appropriate immune balance, etc
What is the endometrial environment?
A set of biochemical and hormonal conditions that prepare and sustain the endometrium to receive and support an embryo.
This enviroment depends on the phase of the cycle the endometrium is in.
Menstrual phase
Endometrial bleeding
Proliferative phase
Endometrial growth
Secretory phase
Receptive endometrium
How do microorganisms affect the endometrium?
The human microbiota refers to the vast community of microorganisms living throughout the body, including the skin, gut, and reproductive system. While these tiny organisms might go unnoticed, they play a vital role in maintaining overall health. In reproduction, the microbiota of both men and women can significantly influence fertility.
For women, the vaginal and endometrial microbiota are key players in creating a healthy environment for conception. Beneficial bacteria, such as lactobacilli, help maintain balance by preventing harmful pathogens from thriving. However, when this balance is disrupted—a condition known as dysbiosis—it can interfere with fertilization and embryo implantation. Understanding the reproductive microbiome is essential for improving fertility outcomes.
Reproductive Health Issues Linked to Dysbiosis
Bacterial Vaginosis (BV): This occurs when harmful bacteria like Gardnerella vaginalis outnumber beneficial lactobacilli, disrupting the vaginal microbiota and impairing conception.
Chronic Endometritis: An imbalance in the endometrial microbiota can cause chronic inflammation, reducing embryo implantation rates and increasing the risk of miscarriage.
Detecting and treating endometrial pathogens increases the chances of pregnancy by
How to detect dysbiosis?
MicroBioMap®, a cutting-edge tool that evaluates the endometrial microbiota using a simple biopsy and advanced PCR (Polymerase Chain Reaction) technology. This test detects the presence of 18 microorganisms, including beneficial bacteria like lactobacilli, providing doctors with critical insights to tailor fertility treatments and improve success rates.
How to detect dysbiosis?
MicroBioMap®, a cutting-edge tool that evaluates the endometrial microbiota using a simple biopsy and advanced PCR (Polymerase Chain Reaction) technology. This test detects the presence of 18 microorganisms, including beneficial bacteria like lactobacilli, providing doctors with critical insights to tailor fertility treatments and improve success rates.
Who developed this test?
Dr Laura Medina, PhD is a senior researcher in the field of Molecular Microbiology and Immunology. She got her PhD in Molecular Microbiology by the Autonomous University of Barcelona in 2012. During her PhD, she focused on the study of enteric microbial pathogens and their interaction with the human host.
In 2013 she joined the Institute of Infection, Immunity and Inflammation of the University of Glasgow, Scotland. There, she set up a research line focused on genetic engineering, which allowed her to study how immune cells migrate and respond to infection and other forms of inflammation.
Dr. Laura Medina, PhD
R&D Scientist IGLS
In 2021, she became a Research Scientist in IGLS. One of her primary research areas at IGLS focuses on the interaction between the endometrial microbiota and the endometrial immune system, and their individual and combined roles in women’s fertility and pregnancy.
Throughout her career, Laura has contributed to five research and development projects funded through competitive grants and her work has led to over 30 scientific publications.
If you want to understand other aspects of fertility:
If you want to understand other aspects of fertility:
Reproductive Microbiota and its Impact on Fertility:
How Diet Influences Reproductive Health
