Scientific and academic papers
Our expert team keeps abreast of industry trends. Open science strategies and academic publications support the research and development of any new techniques and processes in benefit of the permanent improvement and extension of our range of genetics and immunology services.
EUPLOID EMBRYOS SELECTED BY AN AUTOMATED TIME-LAPSE SYSTEM HAVE SUPERIOR SET OUTCOMES THAN SELECTED SOLELY BY CONVENTIONAL MORPHOLOGY ASSESSMENT
Journal of Assisted Reproduction and Genetics. 2018
Rocafort E, Enciso M, Leza A, Sarasa J, Aizpurua J.
Clinical application of a protocol based on universal next-generation sequencing for the diagnosis of beta-thalassaemia and sickle cell anaemia in preimplantation embryos
RBM online. 2018
Kubikova N, Babariya D, Sarasa J, Spath K, Alfarawati S, Wells D.
Oral antioxidant therapy improves sperm quality in patients with abnormally high levels of apoptotic spermatozoa
Hum Reprod. 2017; 32 (supp 1): i184.
Leza A, Rocafort E, Vilella I, Medrano L, Sarasa J, Enciso M, Aizpurua J.
New permeable cryoprotectant-free vitrification method for native human sperm
Hum Reprod. 2017 Oct 1;32(10):2007-2015
Aizpurua J, Medrano L, Enciso M, Sarasa J, Romero A, Fernández MA, Gómez-Torres MJ
ER Map: a new comprehensive and reliable endometrial receptivity test
Hum Reprod. 2016; 31 (supp 1): i49
Development of a new comprehensive and reliable endometrial receptivity map (ER Map/ER Grade) based on RT-qPCR gene expression analysis
Hum Reprod. 2018; Feb 1;33(2):220-228
Enciso M, Carrascosa JP, Sarasa J, Martínez-Ortiz PA, Munné S, Horcajadas JA, Aizpurua J.
Personalised scheduling of embryo transfer at the moment of highest endometrial receptivity according to ER Map® test significantly improves clinical outcomes
Hum Reprod. 2017; 32 (supp 1): i135.
Sarasa J, Aizpurua J, Jurado I, Rodriguez-Estrada B, Garcia-Poyo MC, Climent AB, Martínez-Ortiz P, Enciso M.
Embryo selection of euploid embryos by an automated time-lapse prediction is superior to conventional morphological analysis: a retrospective study
Hum Reprod. 2017; 32 (supp 1): i430
ER Map allow the reliable determination of the window of implantation in infertile women
Fertil Steril. 2016; 106 (3): e216
Horcajadas JA, Enciso M, Sarasa J, Carrascosa JP, Martinez P, Aizpurua J, Munne S
Design, validation and clinical application of a novel nextgeneration sequencing protocol for detection of mitochondrial disease and simultaneous aneuploidy screening in preimplantation embryos
Hum Reprod. 2016; 31 (supp 1) i51
Cutting-edge technology
and science at the service of
reproductive medicine.
Influence of sperm parameters on embryonic development, morphokinetics, and ART outcomes: male factor exploration in a female factor-controlled study platform
Hum Reprod. 2016; 31 (supp 1): i82
Combined time lapse imaging and preimplantation genetic screening: a valuable strategy for embryo selection
Hum Reprod. 2016; 31 (supp 1): i406
Oral antioxidant therapy improves sperm quality in patients with abnormally high levels of apoptotic spermatozoa
Hum Reprod. 2017; 32 (supp 1): i184.
Leza A, Rocafort E, Vilella I, Medrano L, Sarasa J, Enciso M, Aizpurua J.
Polymorphisms in the MTHFR gene influence embryo viability and the incidence of aneuploidy
Hum Genet. 2016;135(5):555-68
Karyomapping identifies second polar body DNA persisting to the blastocyst stage: Implications for embryo biopsy
RBM Online. 2015. 31(6):776–782
Conventional sperm analysis: is it telling us the whole story?
Hum Reprod. 2016; 31 (supp 1): i167
Development of a universal method for the preimplantation diagnosis of β-thalassemia and sickle-cell anaemia using a novel next-generation sequencing approach: a new paradigm for PGD
Hum Reprod. 2016; 31 (supp 1) i402
Embryo selection of euploid embryos by an automated time-lapse prediction is superior to conventional morphological analysis: a retrospective study
Hum Reprod. 2017; 32 (supp 1): i430
Karyomapping allows preimplantation genetic diagnosis of a de-novo deletion undetectable using conventional PGD technology
RBM Online. 2015. 31(6):770-775
Specific alleles of the PRDM9 gene are a risk factor for the production of chromosomally abnormal embryos in humans
Hum Reprod. 2013; 28 (suppl1): i108
Cutting-edge technology
and science at the service of
reproductive medicine.
The origin and impact of embryonic aneuploidy
Hum Genet. 2013;132(9):1001-13
Sperm Chromatin Integrity, DNA Fragmentation and Male Infertility
New Developments in Chromatin Research. pág. 59 – 82. Nova Science Publishers Inc. 2012
Application of an optimised two tailed comet assay on human cumulus cells
Hum Reprod. 2011; 26 (suppl1): i350
Major morphological sperm abnormalities in the bull are correlated with sperm DNA damage
Theriogenology. 2011;76(1):23-32
Enciso M, Cisale H, Jonhston SD, Sarasa J, Fernández JL, Gosálvez J
Effects of density gradient centrifugation and swim up techniques on sperm DNA integrit
Hum Reprod. 2010;25 (suppl1):i127
Increased numbers of DNA-damaged spermatozoa in samples presenting an elevated rate of numerical chromosome abnormalities
Human Reproduction. 2013 Jun;28(6):1707-15
Development of a novel synthetic oligopeptide for the detection of DNA damage in human spermatozoa
Hum Reprod. 2012;27(8):2254-66
The ability of sperm selection techniques to remove single or double-strand DNA damage
Asian J Androl. 2011;13(5):764-8
Differential resistance of mammalian sperm chromatin to oxidative stress as assessed by a two-tailed comet assay
Reprod Fertil Dev. 2011;23(5):633-7
A two-tailed Comet assay for assessing DNA damage in spermatozoa
Reprod Biomed Online. 2009; 18 (5): 609-16
Cutting-edge technology
and science at the service of
reproductive medicine.
Sperm DNA Fragmentation in Rams Vaccinated with Miloxan
Open Vet Sci J. 2008; 2:7-10
A new method to analyze boar sperm DNA fragmentation under bright-field or fluorescence microscopy
Theriogenology. 2006; 65(2):308-16
Halosperm is an easy, available, and cost-effective alternative for determining sperm DNA fragmentation
Fertil Steril. 2005; 84(4):860
Sperm DNA fragmentation in boars is delayed or abolished by using sperm extenders
Theriogenology. 2006; 66(9):2137-43on. 2013 Jun;28(6):1707-15
Infertile men with varicocele show a high relative proportion of sperm cells with intense nuclear damage level, evidenced by the sperm chromatin dispersion test
J Androl. 2006; 27(1):106-11